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1. Her search for love has often caused her excruciating misery and loneliness.

她对爱情的寻觅常常给她带来极大的痛苦和孤独感。

2. Loneliness can be horrible, but it need not remain that way.

孤独可能会很可怕，但也并非一定如此。

3. Many deaf people have feelings of isolation and loneliness.

很多失聪者都有孤独无助的感觉。

4. I am at the beginning of a new and unutterable loneliness.

我再次陷入莫名的孤独寂寞中。

5. They frequently plumb the depths of loneliness, humiliation and despair.

他们常常陷入孤独、屈辱和绝望的深渊。